PhD Defence Giuliana Ventriglia

April 20, 2018
🎓 Congratulations, Dr. Ventriglia! On the successful defense of her joint PhD between KU Leuven and Università degli Studi di Siena (UNISI, Siena, Italy), entitled “Assessing the relevance of a target organ-specific microRNA signature in type 1 diabetes.” This work was carried out under the supervision of Chantal Mathieu (promoter, KU Leuven) and Francesco Dotta (co-promoter, UNISI), with the jury chaired by Lorenzo Leoncini (UNISI) and further contributions from Xavier Bossuyt (Clinical and Diagnostic Immunology, KU Leuven, Leuven, Belgium), Ingrid Arijs (Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Belgium), Elisabetta Ferretti (University of Rome, Rome, Italy), and Romano Regazzi (Université de Lausanne, Lausanne, Switzerland).
Share this post

PhD Research Summary - Dr. Ventriglia

Type 1 diabetes develops after immune-mediated destruction of insulin-producing beta cells, and clinical symptoms appear only after most beta cells are lost. Reliable biomarkers are needed to monitor disease progression and evaluate therapy.

This thesis explored microRNAs (miRNAs), stable small RNA molecules found in blood and other fluids, as potential biomarkers. Using the NOD mouse model, the work investigated whether circulating miRNAs reflect pancreatic immune events and whether they can predict therapeutic efficacy, highlighting their promise for diagnosis and prognosis in autoimmune diabetes.

More information can be found via the link.

Support us

Choose to make a direct impact by contributing to a specific research project or by supporting the overarching goals of the Hippo & Friends Type 1 Diabetes Fund. 

By donating today, you enable early-career scientists to pursue groundbreaking research aimed at preventing and curing type 1 diabetes.
Every contribution moves us one step closer to breakthroughs that matter.

I want to make a direct donationI want to support Hippo & Friends